Brain Goop Traps Hunger Neurons, Fuels Obesity

Research on mice reveals that a sticky goo in the brain's appetite-control center may worsen diabetes and obesity by trapping neurons and blocking insulin. High-fat, high-sugar diets lead to this buildup, impairing insulin's ability to regulate hunger. However, removing the goo helped mice lose weight and improved insulin uptake. This study suggests targeting the cellular scaffolding around neurons could offer new treatment avenues for metabolic disorders. Further research is needed to explore its relevance in humans.